Report on the Fourth Mitsui Chemicals International Symposium on Catalysis Science (MICS2009)

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Invited Lecture

Prof. Barry M. Trost (Stanford University, U.S.A.)

On Inventing Reactions for Atom Economy
Barry M.Trost

Prof. Trost's career has ranged over the entire field of organic synthesis and his research interests include the invention and development of atom economic reactions that are based upon transition metal catalysts and their use to define strategies that result in the total synthesis of complex molecules largely of biological significance. Prof. Trost is the original proponent of the atom economy*.

In this lecture, Prof. Trost discussed atomic economic methodologies that center on redox isomerization reactions on ruthenium catalyzed processes, and the coupling reaction of alkene-alkyne couplings, and the total synthesis of bryostatin using atom economic methodologies.

Atom economy: That proportion of all atomic conversion efficiency in the chemical process. The atom economic process shows the least waste and is eco-friendly.
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