Report on the Fourth Mitsui Chemicals International Symposium on Catalysis Science (MICS2009)

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Mitsui Chemicals Catalysis Science Award of Encouragement Commemorative Lecture

Lecturing Prof. Shigeki Matsunaga (The University of Tokyo, Japan)

Development of Multimetallic Asymmetric Catalysis through Chiral Ligand Design
Lecturing Prof. Shigeki Matsunaga

Dr. Matsunaga developed the concept of “multimetallic concerto asymmetric catalysis”. He designed chiral catalysts with two or more metal centers with different properties, where one metal center functions as a Lewis acid to activate an electrophile, and the other metal interacts with a nucleophile to control its orientation.
This innovative concept is different from traditional catalyst design, and has opened up new possibilities in asymmetric synthesis.

In this lecture, Dr. Matsunaga revealed the concept of multimetallic concerto catalysis, and the chiral design based upon this, and the synthetic application to biologically active compounds.

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